TJP1 Proteine (TJP1)

Bezeichnung:
Tight Junction Protein 1 (Zona Occludens 1) Proteine (TJP1)
Auf www.antikoerper-online.de finden Sie aktuell 9 Tight Junction Protein 1 (Zona Occludens 1) (TJP1) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TJP1 Antikörper (97) und TJP1 Kits (39) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 151 TJP1 Produkte verfügbar.
Synonyme:
ZO-1, zo1
alle Proteine anzeigen Gen GeneID UniProt
TJP1 7082 Q07157
Maus TJP1 TJP1 21872 P39447
TJP1 292994  

Weitere Synonyme anzeigen

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Weitere Proteine zu TJP1 Interaktionspartnern

Human Tight Junction Protein 1 (Zona Occludens 1) (TJP1) Interaktionspartner

  1. Aberrant expression of the tight junction molecules claudin-1 (zeige CLDN7 Proteine) and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma cells.

  2. ZO-1-occludin (zeige OCLN Proteine) interactions regulate multiple phases of epithelial polarization by providing cell-intrinsic signals that are required for single lumen formation.

  3. It is postulated that ZO-1, when not phosphorylated by PKC (zeige PRRT2 Proteine), keeps Octn2 (zeige SLC22A5 Proteine) in an active state, while elimination of this binding in DeltaPDZ mutant or after ZO-1 phosphorylation leads to diminution of Octn2 (zeige SLC22A5 Proteine) activity.

  4. Results uncovered ZO-1 as part of a signaling node activated by VEGF (zeige VEGFA Proteine), but not Ang-1 (zeige ANGPT1 Proteine), that specifically modulates endothelial cells proliferation during angiogenesis.

  5. Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (zeige MLXIP Proteine)-34c bound together to regulate the expressions of MAZ (zeige MAZ Proteine), ZO-1 and occludin (zeige OCLN Proteine).

  6. STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.

  7. Data show that tight junction protein 1 (TJP1) suppressed expression of the catalytically proteasome subunits LMP7 (zeige PSMB8 Proteine) and LMP2 (zeige PSMB9 Proteine), decreased proteasome activity, and enhanced proteasome inhibitor sensitivity in vitro and in vivo through suppression of EGFR (zeige EGFR Proteine)/JAK1 (zeige JAK1 Proteine)/STAT3 (zeige STAT3 Proteine) signaling.

  8. ZO-1 highly expresses in cell-cell junctions and is related to odontoblast differentiation, which may contribute to dental pulp repair or even the formation of an odontoblast layer.

  9. this study shows that the expression and the immunoreactivity of ZO-1 is decreased in the nasal epithelium of patients with allergic rhinitis

  10. The frequency of alleles and genotypes of rs2291166 gene polymorphism TJP1 was determined in the Mexico Mestizos population. The ancestral allele was the most prevalent. The conformational effect of this amino acid change was performed in silico.

Mouse (Murine) Tight Junction Protein 1 (Zona Occludens 1) (TJP1) Interaktionspartner

  1. STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.

  2. Cx43 (zeige GJA1 Proteine) tethers the F-actin cytoskeleton through a ZO-1 linker and supports cell spreading and exploration during locomotion in cerebral endothelial cells.

  3. Expression of Podocalyxin (zeige PODXL Proteine), which positively regulates the formation of microvilli and the apical membrane, is repressed in embryoid bodies lacking both ZO-1 and ZO-2 (zeige TJP2 Proteine) and this correlates with an aberrant submembranous localization of Ezrin (zeige EZR Proteine).

  4. Zonula occludens-1, occludin (zeige OCLN Proteine) and E-cadherin (zeige CDH1 Proteine) expression and organization in salivary glands

  5. Tjp1 expression was decreased in glomerular diseases in human and animal models, our results indicate that the suppression of Tjp1 could directly aggravate glomerular disorders, highlights Tjp1 as a potential therapeutic target.

  6. Arecoline increases the production of TNF-alpha (zeige TNF Proteine) and induces protein redistribution of ZO-1.

  7. Vcl (zeige VCL Proteine) plays a crucial role in stabilizing gap junctions and myocyte integrity through direct interactions with ZO-1 and stabilization of CX43 (zeige GJA1 Proteine).

  8. Activation of RhoA (zeige RHOA Proteine)/ROCK1 (zeige ROCK1 Proteine) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin (zeige OCLN Proteine)/ZO-1, which can be corrected by simvastatin.

  9. Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C epsilon (zeige PRKCE Proteine)-mediated zona occludens-1 phosphorylation at threonine 770/772.

  10. The JAM-A (zeige F11R Proteine) and ZO-1 genes were highly expressed in all the tested tissues.

Cow (Bovine) Tight Junction Protein 1 (Zona Occludens 1) (TJP1) Interaktionspartner

  1. cyclic strain modulates both the expression and phosphorylation state of occludin (zeige OCLN Proteine) and ZO-1 in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity

Pig (Porcine) Tight Junction Protein 1 (Zona Occludens 1) (TJP1) Interaktionspartner

  1. ZO-1 and occludin (zeige OCLN Proteine) are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin (zeige OCLN Proteine) at the blastocyst stage.

TJP1 Protein Überblick

Protein Überblick

This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with TJP1

  • tight junction protein 1 (TJP1)
  • tight junction protein 1 (Tjp1)
  • tight junction protein 1 (ZO1)
  • tight junction protein 1 (zona occludens 1) (TJP1)
  • zonula occludens 1 (ZO1)
  • ZO-1 Protein
  • zo1 Protein

Bezeichner auf Proteinebene für TJP1

tight junction protein ZO-1 , zona occludens 1 , zona occludens protein 1 , zonula occludens 1 protein , zonula occludens protein 1 , tight junction protein 1 (zona occludens 1) , zonula occludens 1

GENE ID SPEZIES
7082 Homo sapiens
21872 Mus musculus
292994 Rattus norvegicus
100346390 Oryctolagus cuniculus
100718142 Cavia porcellus
407102 Bos taurus
443200 Ovis aries
101082238 Felis catus
403752 Canis lupus familiaris
415388 Gallus gallus
396567 Sus scrofa
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