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anti-FK506 Binding Protein 8, 38kDa (FKBP8) Antikörper

Bezeichnung:
anti-FK506 Binding Protein 8, 38kDa Antikörper (FKBP8)
Auf www.antikoerper-online.de finden Sie aktuell 113 FK506 Binding Protein 8, 38kDa (FKBP8) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen FK506 Binding Protein 8, 38kDa Proteine (7) und FK506 Binding Protein 8, 38kDa Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 133 FK506 Binding Protein 8, 38kDa Produkte verfügbar.
Synonyme:
38kDa, FKBP-8, FKBP-38, fkbp8, FKBP38, FKBPr38, zgc:77672

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Am meisten referenzierte anti-FK506 Binding Protein 8, 38kDa Antikörper

  1. Cow (Bovine) Polyclonal FKBP8 Primary Antibody für WB - ABIN2782773 : Okamoto, Omori, Kaname, Abe, Nishimura, Suzuki, Miyamura, Yoshimori, Moriishi, Matsuura: A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication. in Journal of virology 2008 (PubMed)

  2. Human Polyclonal FKBP8 Primary Antibody für EIA, WB - ABIN401051 : Portier, Taglialatela: Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression. in The Journal of biological chemistry 2006 (PubMed)

Weitere Antikörper gegen FK506 Binding Protein 8, 38kDa Interaktionspartner

Mouse (Murine) FK506 Binding Protein 8, 38kDa (FKBP8) Interaktionspartner

  1. Our findings thus indicate that the FKBP38-ANKMY2 (zeige ANKMY2 Antikörper) axis plays a key role in regulation of Shh (zeige SHH Antikörper) signaling in vivo.

  2. In pre-hearing time Fkbp8-specific signal was also observed in the tectorial membrane, whose alpha- and beta-Tectorin (zeige TECTB Antikörper) components show similar time-dependent expression of mRNA as Fkbp8.

  3. used systemic gene transfer in tumor-bearing mice to identify novel antiinvasive and antimetastatic functions for Fkbp8, and subsequently for Fkbp1a (zeige FKBP1A Antikörper).

  4. Results show that FKBP8 is an essential antagonist of sonic hedgehog (zeige SHH Antikörper) signaling in central nervous system development.

  5. FKBP38 functions to anchor the 26S proteasome (zeige Psmd4 Antikörper) at the organellar membrane

  6. Gene expression analysis of Fkbp8 mutants revealed a perturbation of expression of neural tube patterning genes, suggesting that endogenous FKBP8 activity establishes dorso-ventral patterning of the neural tube.

  7. Findings suggest that FKBP38 is required for neuroectodermal organization during neural tube formation as a result of its anti-apoptotic activity and regulation of neurite extension

  8. Disruption of FKBP8 function activates the Shh (zeige SHH Antikörper) signaling pathway cell-autonomously dependent on the Gli2 (zeige GLI2 Antikörper) transcription factor and kinesin-2 (zeige KIF2A Antikörper) subunit Kif3a (zeige KIF3A Antikörper), a component of the intraflagellar transport machinery used to generate cilia.

  9. Data indicate that PHD2 (zeige EGLN1 Antikörper) protein stability is regulated by a ubiquitin-independent proteasomal pathway involving FKBP38 as adaptor protein that mediates proteasomal interaction.

Human FK506 Binding Protein 8, 38kDa (FKBP8) Interaktionspartner

  1. The information presented here provides important clues for understanding the catalytic activity of FKBP38, its regulation by the unique N-terminal extension, and the potential calcium- and calmodulin (zeige CALM1 Antikörper)-mediated activation of FKBP38.

  2. Overexpression of permanently active S100P (zeige S100P Antikörper) in Huh-7 cells inhibited the interaction of FKBP38 with Bcl-2 (zeige BCL2 Antikörper), resulting in the suppression of Bcl-2 (zeige BCL2 Antikörper) stability

  3. FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR (zeige CFTR Antikörper)) folding and stability

  4. The derived structure model of the complex between Bcl-2 (zeige BCL2 Antikörper) and the FKBP38 catalytic domain features both electrostatic and hydrophobic intermolecular contacts and provides a rationale for the regulation of the FKBP38/Bcl-2 (zeige BCL2 Antikörper) interaction by Ca(2 (zeige CA2 Antikörper)+).

  5. Data support a dual role for FKBP38 in regulating CFTR (zeige CFTR Antikörper) synthesis and post-translational folding.

  6. a dual mechanism for PA activation of mTORC1: PA displaces FKBP38 from mTOR (zeige FRAP1 Antikörper) and allosterically stimulates the catalytic activity of mTORC1.

  7. this charge-sensitive site in the FKBP (zeige FKBP7 Antikörper) domain participates in the regulation of FKBP38 function by enabling electrostatic interactions with ligand proteins and/or salt ions such as Ca(2 (zeige CA2 Antikörper)+)

  8. These results demonstrate that FKBP38 is a novel regulator of the oncogenic protein PRL-3 abundance and that alteration in the stability of PRL-3 can have a dramatic impact on cell proliferation.

  9. novel insights into the structural arrangement of FKBP38/calmodulin (zeige CALM1 Antikörper) complex

  10. FKBP38 is a key player in regulating the function of Bcl-2 (zeige BCL2 Antikörper) by antagonizing caspase (zeige CASP3 Antikörper)-dependent degradation through the direct interaction with the flexible loop domain of Bcl-2 (zeige BCL2 Antikörper), which contains the caspase (zeige CASP3 Antikörper) cleavage site

FK506 Binding Protein 8, 38kDa (FKBP8) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.

Alternative names and synonyms associated with FK506 Binding Protein 8, 38kDa (FKBP8)

  • FK506 binding protein 8, 38kDa (FKBP8) Antikörper
  • FK506 binding protein 8, 38kDa (fkbp8) Antikörper
  • FK506-binding protein 8 (fkbp8) Antikörper
  • FK506 binding protein 8 (Fkbp8) Antikörper
  • FK506 binding protein 8 (fkbp8) Antikörper
  • 38kDa Antikörper
  • FKBP-8 Antikörper
  • FKBP-38 Antikörper
  • fkbp8 Antikörper
  • FKBP38 Antikörper
  • FKBPr38 Antikörper
  • zgc:77672 Antikörper

Bezeichner auf Proteinebene für FKBP8

peptidyl-prolyl cis-trans isomerase FKBP8 , FK506 binding protein 8, 38kDa , peptidyl-prolyl cis-trans isomerase FKBP8-like , FK506-binding protein 8 , 38 kDa FK506-binding protein , 38 kDa FKBP , FK506-binding protein 38 , FKBPR38 , PPIase FKBP8 , mFKBP38 , rotamase , FK506-binding protein 8 (38kD) , FKBP-38 , FKBP-8 , hFKBP38

GENE ID SPEZIES
420123 Gallus gallus
455862 Pan troglodytes
100145724 Xenopus (Silurana) tropicalis
100443356 Pongo abelii
100194916 Salmo salar
14232 Mus musculus
290652 Rattus norvegicus
393858 Danio rerio
23770 Homo sapiens
484819 Canis lupus familiaris
512356 Bos taurus
495188 Xenopus laevis
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