anti-Maus TREX1 Antikörper für Enzyme Immunoassay

Recommended TREX1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
three Prime Repair Exonuclease 1 (TREX1) Antikörper
  • AGS1
  • CRV
  • DRN3
  • HERNS
  • 1661
  • AU041952
  • RGD1309596
  • three prime repair exonuclease 1
  • CpipJ_CPIJ012074
  • Tsp_03749
  • TREX1
  • Trex1
Epitop
Center
5
4
4
3
3
3
3
3
2
2
2
2
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
70
11
8
Wirt
Kaninchen
44
29
Klonalität
Polyklonal
Konjugat
Dieser TREX1 Antikörper ist unkonjugiert
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
66
37
26
24
18
16
5
2
1
1
Hersteller
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Produktnummer ABIN5555375
$ 375.38
Zzgl. Versandkosten $45.00

General

Antigen three Prime Repair Exonuclease 1 (TREX1) Antikörper
Epitop Center
(5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(70), (11), (8)
Wirt Kaninchen
(44), (29)
Klonalität
Polyklonal
Konjugat Dieser TREX1 Antikörper ist unkonjugiert
(3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(66), (37), (26), (24), (18), (16), (5), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TREX1 Antikörper

Target Details TREX1 Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects TREX1. It will not cross-react with the related protein TREX2.
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse, rat
Reinigung Affinity chromatography
Immunogen TREX1 antibody was raised against a 15 amino acid peptide near the center of human TREX1.
Isotyp IgG

Target Details TREX1

Produktdetails anti-TREX1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TREX1 (TREX1 Antibody Abstract)
Hintergrund Trex1 is the major human 3\' to 5\' exonuclease which is required for checkpoint signaling after DNA damage. It is ubiquitously expressed, binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage and recruits the ataxia telangiectasia and Rad3 related protein (ATR), a checkpoint kinase, to sites of DNA damage and replication stress. Trex1 is required for ATR expression. This gene uses two different open reading frames. The upstream ORF encodes proteins which interact with ATR and localize to intranuclear foci induced by DNA damage and are essential components of the DNA damage checkpoint. The downstream ORF encodes proteins with 3\' to 5\' exonuclease activity and may be a subunit of human DNA polymerase III. Multiple transcript variants encoding different isoforms have been found. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis.Synonyms: 3'-5' exonuclease TREX1, DNase III, Three prime repair exonuclease 1
Gen-ID 11277
NCBI Accession NP_057465
Forschungsgebiet DNA/RNA, Immunology
Pathways Apoptose

Anwendungsinformationen

Produktdetails anti-TREX1 Antikörper Target Details TREX1 Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TREX1 Antikörper Target Details TREX1 Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 0.02 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.