Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ENAH Antikörper (AA 415-541)

ENAH Reaktivität: Human, Maus, Ratte, Huhn WB, IHC, IP, IF Wirt: Maus Monoclonal 21-Mena unconjugated
Produktnummer ABIN968115
  • Target Alle ENAH Antikörper anzeigen
    ENAH (Enabled Homolog (ENAH))
    Bindungsspezifität
    • 13
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 415-541
    Reaktivität
    • 45
    • 21
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Huhn
    Wirt
    • 41
    • 4
    Maus
    Klonalität
    • 41
    • 4
    Monoklonal
    Konjugat
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ENAH Antikörper ist unkonjugiert
    Applikation
    • 44
    • 20
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Ratte (Rattus), Huhn
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Mouse Mena aa. 415-541
    Klon
    21-Mena
    Isotyp
    IgA
    Top Product
    Discover our top product ENAH Primärantikörper
  • Kommentare

    Related Products: ABIN968552, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Howe, Hogan, Juliano: "Regulation of vasodilator-stimulated phosphoprotein phosphorylation and interaction with Abl by protein kinase A and cell adhesion." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38121-6, (2002) (PubMed).

    García Arguinzonis, Galler, Walter, Reinhard, Simm: "Increased spreading, Rac/p21-activated kinase (PAK) activity, and compromised cell motility in cells deficient in vasodilator-stimulated phosphoprotein (VASP)." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45604-10, (2002) (PubMed).

    Drees, Friederich, Fradelizi, Louvard, Beckerle, Golsteyn: "Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins." in: The Journal of biological chemistry, Vol. 275, Issue 29, pp. 22503-11, (2000) (PubMed).

    Gertler, Niebuhr, Reinhard, Wehland, Soriano: "Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics." in: Cell, Vol. 87, Issue 2, pp. 227-39, (1996) (PubMed).

  • Target
    ENAH (Enabled Homolog (ENAH))
    Andere Bezeichnung
    Mena (ENAH Produkte)
    Synonyme
    ENA antikoerper, MENA antikoerper, NDPP1 antikoerper, AI464316 antikoerper, AW045240 antikoerper, Mena antikoerper, Ndpp1 antikoerper, WBP8 antikoerper, id:ibd2798 antikoerper, si:ch211-215p14.1 antikoerper, zgc:103638 antikoerper, ENAH, actin regulator antikoerper, enabled homolog (Drosophila) antikoerper, Enah antikoerper, ENAH antikoerper, enah antikoerper
    Hintergrund
    Abl and Disabled (Dab) are essential for correct axonal connections during Drosophila development. Mutations in Enabled (Ena) rescue the genetic defects caused by mutated Abl and Dab. Mena (Mammalian Ena) is a protein with significant homology to Eva, VASP, and WASP proteins. The murine Mena gene predicts a protein of 541 amino acids. However, two additional exons that could introduce 246 amino acids onto the C-terminal region have been identified. Homology searches identified two EVH domains (Ena-Vasp homology), one near each terminus of Mena. Antibodies to Mena detect 80 kDa, 88 kDa, and 140 kDa protein with the 80 kDa and 88 kDa proteins being widely expressed and the 140 kDa protein reportedly mainly found in brain tissue. Like VASP, Mena is localized to focal contacts and, when ectopically expressed, induces the formation of F-actin outgrowths in fibroblasts. This antibody is routinely tested by Western blot analysis.
    Synonyms: Mammalian Ena (Enabled)
    Molekulargewicht
    140, 88, 80 kDa
Sie sind hier:
Kundenservice