HSC70 Interacting Protein HIP Antikörper

Produktnummer ABIN967083

Produktdetails anti-HSC70 Interacting Protein HIP Antikörper

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSC70 Interacting Protein HIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human ST13 expressed in E. Coli.

Klon: 3B10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-HSC70 Interacting Protein HIP Antikörper (ABIN967083)

Velten, Gomez-Vrielynck, Chaffotte, Ladjimi: "Domain structure of the HSC70 cochaperone, HIP." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 259-66, (2002) (PubMed).

Details zu HSC70 Interacting Protein HIP

Target: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Andere Bezeichnung: ST13 (ST13 Produkte)

Synonyme: CG32789 antikoerper, Dmel\\CG32789 antikoerper, anon-EST:fe1A9 antikoerper, 1110007I03Rik antikoerper, 3110002K08Rik antikoerper, AW555194 antikoerper, HIP antikoerper, HOP antikoerper, HSPABP antikoerper, HSPABP1 antikoerper, PRO0786 antikoerper, SNC6 antikoerper, p48 antikoerper, AAG2 antikoerper, FAM10A1 antikoerper, FAM10A4 antikoerper, P48 antikoerper, Hsc/Hsp70-interacting protein antikoerper, suppression of tumorigenicity 13 antikoerper, ST13, Hsp70 interacting protein antikoerper, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) antikoerper, HIP antikoerper, St13 antikoerper, ST13 antikoerper

Hintergrund: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several cochaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.
Synonyms: HIP, HOP, P48, AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST13

Molekulargewicht: 48kDa

Gen-ID: 6767