MMP10 Antikörper (C-Term)

Produktnummer ABIN966586

Produktdetails anti-MMP10 Antikörper

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Bindungsspezifität: AA 410-422, C-Term

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Polyklonal

Konjugat: Dieser MMP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human MMP-10 (410-422 aa), identical to the related mouse and rat sequence.

Anwendungsinformationen

Applikationshinweise: WB: The detection limit for MMP-10 is approximately 2.5ng/lane under non-reducing and reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Lagerung: -20 °C

Referenzen für anti-MMP10 Antikörper (ABIN966586)

Jung, Warter, Rumpler: "Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization." in: Annales de génétique, Vol. 33, Issue 1, pp. 21-3, (1990) (PubMed).

Muller, Quantin, Gesnel, Millon-Collard, Abecassis, Breathnach: "The collagenase gene family in humans consists of at least four members." in: The Biochemical journal, Vol. 253, Issue 1, pp. 187-92, (1988) (PubMed).

Details zu MMP10

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Andere Bezeichnung: MMP-10 (MMP10 Produkte)

Synonyme: SL-2 antikoerper, STMY2 antikoerper, AV377895 antikoerper, MMP-10 antikoerper, matrix metallopeptidase 10 antikoerper, MMP10 antikoerper, Mmp10 antikoerper

Hintergrund: Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.