FOXO1 Antikörper

Produktnummer ABIN966149

Produktdetails anti-FOXO1 Antikörper

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Spezifität: FKHR (Ab-319) antibody detects endogenous levels of total FKHR protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR around the phosphorylation site of serine 319.

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000
IHC: 1:50~1:100.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-FOXO1 Antikörper (ABIN966149)

Zhao, Gan, Pan, Kan, Majeski, Adam, Unterman: "Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 839-49, (2004) (PubMed).

Rena, Woods, Prescott, Peggie, Unterman, Williams, Cohen: "Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion." in: The EMBO journal, Vol. 21, Issue 9, pp. 2263-71, (2002) (PubMed).

Rena, Prescott, Guo, Cohen, Unterman: "Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting." in: The Biochemical journal, Vol. 354, Issue Pt 3, pp. 605-12, (2001) (PubMed).

Guo, Rena, Cichy, He, Cohen, Unterman: "Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence." in: The Journal of biological chemistry, Vol. 274, Issue 24, pp. 17184-92, (1999) (PubMed).

Details zu FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Andere Bezeichnung: FKHR (FOXO1 Produkte)

Synonyme: FKH1 antikoerper, FKHR antikoerper, FOXO1A antikoerper, FoxO1a.1 antikoerper, foxo1 antikoerper, zgc:153388 antikoerper, Fkhr antikoerper, Foxo1a antikoerper, AI876417 antikoerper, Afxh antikoerper, Fkhr1 antikoerper, fkh1 antikoerper, fkhr antikoerper, foxo1a antikoerper, xFoxO1 antikoerper, FoxO1A antikoerper, foxo1a.2 antikoerper, forkhead box O1 antikoerper, forkhead box O1 a antikoerper, forkhead box O1 L homeolog antikoerper, forkhead box O1 b antikoerper, FOXO1 antikoerper, foxo1a antikoerper, Foxo1 antikoerper, foxo1 antikoerper, foxo1.L antikoerper, foxo1b antikoerper

Pathways: PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling