TIFA antikoerper, xtifa antikoerper, T2BP antikoerper, T6BP antikoerper, TIFAA antikoerper, T2bp antikoerper, Ab2-389 antikoerper, TRAF interacting protein with forkhead associated domain antikoerper, TRAF-interacting protein with forkhead-associated domain antikoerper, TRAF-interacting protein with forkhead-associated domain S homeolog antikoerper, TIFA antikoerper, tifa antikoerper, Tifa antikoerper, tifa.S antikoerper
Hintergrund
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.Synonyms: Putative MAPK-activating protein PM14, Putative NF-kappa-B-activating protein 20, TRAF-interacting protein with FHA domain-containing protein A, TRAF2-binding protein