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TBC1D3E (AA 497-527), (C-Term) Antikörper

Details zu Produkt Nr. ABIN955097, Anbieter: Anmelden zum Anzeigen
Antigen
Epitop
C-Term, AA 497-527
11
7
3
Reaktivität
Human
12
Wirt
Kaninchen
12
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
11
8
Hersteller
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Immunogen KLH conjugated synthetic peptide between 497-527 amino acids from the C-terminal region of human TBC1D3E
Isotyp Ig
Spezifität This antibody reacts to TBC1D3E.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity chromatography on Protein A
Hintergrund BC1D3E acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).Synonyms: TBC1 domain family member 3E/3F
Molekulargewicht 62199 Da
Gen-ID 84218
NCBI Accession NP_115634
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for anti-TBC1D3E (AA 497-527), (C-Term) Antikörper (ABIN955097) TBC1D3E Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35µg/l...
Allgemeine Veröffentlichungen Alkan, Kidd, Marques-Bonet, Aksay, Antonacci, Hormozdiari, Kitzman, Baker, Malig, Mutlu, Sahinalp, Gibbs, Eichler: "Personalized copy number and segmental duplication maps using next-generation sequencing." in: Nature genetics, Vol. 41, Issue 10, pp. 1061-7, 2009

Wainszelbaum, Charron, Kong, Kirkpatrick, Srikanth, Barbieri, Gygi, Stahl: "The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking." in: The Journal of biological chemistry, Vol. 283, Issue 19, pp. 13233-42, 2008

Hodzic, Kong, Wainszelbaum, Charron, Su, Stahl: "TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12." in: Genomics, Vol. 88, Issue 6, pp. 731-6, 2006

Zody, Garber, Adams, Sharpe, Harrow, Lupski, Nicholson, Searle, Wilming, Young, Abouelleil, Allen, Bi, Bloom, Borowsky, Bugalter, Butler, Chang, Chen, Cook, Corum, Cuomo, de Jong, DeCaprio, Dewar et al.: "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. ..." in: Nature, Vol. 440, Issue 7087, pp. 1045-9, 2006

Paulding, Ruvolo, Haber: "The Tre2 (USP6) oncogene is a hominoid-specific gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2507-11, 2003