RFXANK Antikörper (Middle Region)

Produktnummer ABIN950419

Produktdetails anti-RFXANK Antikörper

Target: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Bindungsspezifität: AA 93-123, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFXANK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human ANKRA1 / RFXANK (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 93-123 amino acids from the Central region of human RFXANK. Genename: RFXANK

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RFXANK

Target: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Andere Bezeichnung: ANKRA1 / RFXANK (RFXANK Produkte)

Synonyme: ANKRA1 antikoerper, BLS antikoerper, F14150_1 antikoerper, RFX-B antikoerper, Tvl1 antikoerper, regulatory factor X associated ankyrin containing protein antikoerper, regulatory factor X-associated ankyrin-containing protein antikoerper, RFXANK antikoerper, Rfxank antikoerper

Hintergrund: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.Synonyms: Ankyrin repeat family A protein 1, DNA-binding protein RFXANK, RFXB, Regulatory factor X subunit B, Regulatory factor X-associated ankyrin-containing protein

Molekulargewicht: 28102 Da

Gen-ID: 8625

NCBI Accession: NP_003712