PSMD14 Antikörper (AA 101-200) (AbBy Fluor® 488)

Produktnummer ABIN905319

Der AbBy Fluor® 488-konjugierte Kaninchen Polyklonal anti-PSMD14 Antikörper (ABIN905319) detektiert spezifisch PSMD14 in IF (cc) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PSMD14 Antikörper (AA 101-200) (AbBy Fluor® 488) (ABIN905319)

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD14 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PSMD14 Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 101-200

Homologie: Human,Mouse,Rat,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PSMD14

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Andere Bezeichnung: Mad1

Hintergrund:

Synonyms: mitosis arrest deficiency 1, hMAD1, HsMAD1, MAD1L1, Mitotic arrest deficient 1, Mitotic checkpoint MAD1 protein homolog, Mitotic spindle assembly checkpoint protein MAD1, PIG9, Tax binding protein 181, TP53I9 , Tumor protein p53 inducible protein 9, TXBP181, MD1L1_HUMAN.

Background: spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization.

Gen-ID: 8379

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway