TFE3 Antikörper (AA 303-307)

Produktnummer ABIN871655

Produktdetails anti-TFE3 Antikörper

Target: TFE3 (Transcription Factor E3 (TFE3))

Bindungsspezifität: AA 303-307

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFE3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody detects endogenous levels of total TFE3 protein.

Aufreinigung: Affinity purified

Immunogen: Peptide sequence around AA 303-307 (L-D-V-Y-S) derived from Human TFE3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu TFE3

Target: TFE3 (Transcription Factor E3 (TFE3))

Andere Bezeichnung: TFE3 (TFE3 Produkte)

Synonyme: RCCP2 antikoerper, RCCX1 antikoerper, TFEA antikoerper, bHLHe33 antikoerper, F830016E06Rik antikoerper, Tcfe3 antikoerper, Tfe-3 antikoerper, RGD1559642 antikoerper, cb873 antikoerper, zgc:109815 antikoerper, transcription factor binding to IGHM enhancer 3 antikoerper, transcription factor E3 antikoerper, transcription factor binding to IGHM enhancer 3 S homeolog antikoerper, transcription factor binding to IGHM enhancer 3a antikoerper, TFE3 antikoerper, Tfe3 antikoerper, tfe3.S antikoerper, tfe3a antikoerper

Hintergrund: Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Molekulargewicht: 70 kDa

Gen-ID: 7030

NCBI Accession: NP_006512

UniProt: P19532