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F-Box and Leucine-Rich Repeat Protein 16 (FBXL16) (C-Term) Antikörper

Details zu Produkt Nr. ABIN783375, Anbieter: Anmelden zum Anzeigen
Antigen
  • BC042620
  • C16orf22
  • c380A1.1
  • Fbl16
  • Scirr1
  • VIER F-box proteine 2
Epitop
C-Term
9
6
2
1
Reaktivität
Human, Maus, Ratte (Rattus)
34
22
22
1
1
Wirt
Kaninchen
34
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
24
11
9
8
7
2
1
1
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Immunogen 18 amino acid peptide near the carboxy terminus of human FBXL16
Spezifität This antibody detects FBXL16 C-term. FBXL16 antibody is predicted to not cross-react with other F-box protein family members.
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse, rat
Reinigung Affinity chromatography purified via peptide column
Andere Bezeichnung FBXL16 (FBXL16 Antibody Abstract)
Hintergrund FBXL16 (F-box and leucine-rich repeat protein 16), a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways.Synonyms: C16orf22, F-box and leucine-rich repeat protein 16, F-box/LRR-repeat protein 16, FBL16
Gen-ID 146330
NCBI Accession NP_699181
UniProt Q8N461
Forschungsgebiet Proteolysis / Ubiquitin
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer PBS containing 0.02 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for anti-F-Box and Leucine-Rich Repeat Protein 16 (FBXL16) (C-Term) Antikörper (ABIN783375) Western blot analysis of FBXL16 in human spleen tissue lysate with FBXL16 antibody at...
Allgemeine Veröffentlichungen Martin, Han, Gordon, Terry, Prabhakar, She, Xie, Hellsten, Chan, Altherr, Couronne, Aerts, Bajorek, Black, Blumer, Branscomb, Brown, Bruno, Buckingham, Callen, Campbell, Campbell, Campbell, Caoile et al.: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004

Jin, Cardozo, Lovering, Elledge, Pagano, Harper: "Systematic analysis and nomenclature of mammalian F-box proteins." in: Genes & development, Vol. 18, Issue 21, pp. 2573-80, 2004