JNK Antikörper (pThr183, pTyr185) (Cy5)

Produktnummer ABIN2177527

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch JNK in WB, IF (p) und IF (cc). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für JNK Antikörper (pThr183, pTyr185) (Cy5) (ABIN2177527)

Target: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JNK Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-JNK Antikörper (Cy5)

Bindungsspezifität: pThr183, pTyr185

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MAPK9 around the phosphorylation site of Thr183+Tyr185

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu JNK

Target: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Andere Bezeichnung: MAPK8 +

Hintergrund:

Synonyms: MAPK8/MAPK9phospho T183/Y185, Mapk9, C Jun kinase 2, C Jun N terminal kinase 2, JNK 2, JNK-2, JNK 55, JNK2 alpha, JNK2 beta, JNK2alpha, JNK2B, JNK2beta, JNK55, Jun kinase, MAP kinase 9, MAPK 9, Mitogen activated protein kinase 9, P54 alpha, P54aSAPK, PRKM9, SAPK alpha, SAPK1a, SAPKa, Stress activated protein kinase JNK2.

Background: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.

Gen-ID: 5601

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteine