PIWIL1 Antikörper (AA 551-650)

Produktnummer ABIN671631

Produktdetails anti-PIWIL1 Antikörper

Target: PIWIL1 (Piwi-Like 1 (PIWIL1))

Bindungsspezifität: AA 551-650

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIWIL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from chicken PIWIL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PIWIL1 Antikörper (ABIN671631)

Liu, Jiang, Zhang: "Expression of PSCA, PIWIL1 and TBX2 and its correlation with HPV16 infection in formalin-fixed, paraffin-embedded cervical squamous cell carcinoma specimens." in: Archives of virology, Vol. 155, Issue 5, pp. 657-63, (2010) (PubMed).

Details zu PIWIL1

Target: PIWIL1 (Piwi-Like 1 (PIWIL1))

Andere Bezeichnung: PIWIL1 (PIWIL1 Produkte)

Synonyme: ziwi antikoerper, PIWI antikoerper, HIWI antikoerper, MIWI antikoerper, piwi like RNA-mediated gene silencing 1 antikoerper, PIWI-like protein 1 antikoerper, putative PIWI-like protein 1 antikoerper, putative argonaut-like protein antikoerper, piwi-like RNA-mediated gene silencing 1 antikoerper, PIWIL1 antikoerper, Tb10.70.5520 antikoerper, LINJ_21_0470 antikoerper, LBRM_21_0470 antikoerper, piwil1 antikoerper, Piwil1 antikoerper

Hintergrund:

Synonyms: PIWI, Piwi-like protein 1, PIWIL1

Background: Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 3 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity).

Gen-ID: 416804

UniProt: A6N7Y9