Factor VIII Antikörper (Coagulation Factor VIII)

Details for Product anti-F8 Antibody No. ABIN668601, Anbieter: Anmelden zum Anzeigen
Antigen
  • fb61d02
  • wu:fb61d02
  • Cf-8
  • Cf8
  • FVIII
  • AHF
  • DXS1253E
  • F8B
  • F8C
  • HEMA
  • coagulation factor VIIi
  • coagulation factor VIII
  • coagulation factor VIII, procoagulant component
  • f7i
  • F8
Reaktivität
Hund, Human, Maus, Ratte (Rattus)
311
69
52
26
11
2
2
2
2
1
1
1
Wirt
Kaninchen
172
137
27
4
1
Klonalität
Polyklonal
Konjugat
Dieser Factor VIII Antikörper ist unkonjugiert
19
18
14
7
7
6
5
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
222
162
52
42
38
25
22
13
13
12
7
6
3
3
3
2
2
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide derived from rat factor VIII
Isotyp IgG
Kreuzreaktivität Human, Hund
Reinigung Purified by Protein A.
Andere Bezeichnung Factor VIII (F8 Antibody Abstract)
Hintergrund

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].

Synonyms: coagulation factor VIII, Ahf, Antihemophilic factor, Coagulation factor VIII, Coagulation factor VIII procoagulent component, Coagulation factor VIIIc, Dna segment on chromosome x unique 1253 expressed sequence, Dxs1253e, F8, F8 protein,F8c, FactorVIII, FVIII, Hema coagulation factor VIIIc procoagulent component, Hemophilia a, Hemophilia classic,

Molekulargewicht 267kDa
Gen-ID 302470
UniProt Q7TN96
Applikationshinweise IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Coagulation Factor VIII (F8) antibody (ABIN668601) Formalin-fixed and paraffin embedded rat tibia tissue labeled with Anti-Factor VIII (...
Immunofluorescence (IF) image for anti-Coagulation Factor VIII (F8) antibody (ABIN668601) Formalin-fixed : Mouse C57 cells labeled with Anti- Factor VIII (FVIII) Polyclonal An...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Coagulation Factor VIII (F8) antibody (ABIN668601) Formalin-fixed and paraffin embedded rat tibia tissue labeled with Anti-Factor VIII (...
Produkt verwendet in: Song, Li, Yu: "Effects of preserving different veins on flow-through flap survival: An experimental study." in: Experimental and therapeutic medicine, Vol. 11, Issue 1, pp. 318-324, 2016 (PubMed).

Lei, Peng, Samuel, Zhang, Wu, Wang, Li, Liu: "A simple and biosafe method for isolation of human umbilical vein endothelial cells." in: Analytical biochemistry, Vol. 508, pp. 15-8, 2016 (PubMed).

Yu, Zhang, Jiang, Wang, Zhang: "Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction." in: Molecular medicine reports, Vol. 12, Issue 5, pp. 6718-26, 2015 (PubMed).

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