Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This NSMAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human NSMAF.
FAN antikoerper, AA959567 antikoerper, C630007J05 antikoerper, Fan antikoerper, protein FAN antikoerper, neutral sphingomyelinase activation associated factor antikoerper, neutral sphingomyelinase (N-SMase) activation associated factor antikoerper, EDI_035100 antikoerper, NSMAF antikoerper, Nsmaf antikoerper
Hintergrund
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.