COL8a2 Antikörper (C-Term)

Produktnummer ABIN655804

Produktdetails anti-COL8a2 Antikörper

Target: COL8a2 (COL8A2) (Collagen, Type VIII, alpha 2 (COL8A2))

Bindungsspezifität: AA 571-599, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL8a2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COL8A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the C-terminal region of human COL8A2.

Klon: RB31742

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-COL8a2 Antikörper (ABIN655804)

Okumura, Minamiyama, Ho, Kay, Kawasaki, Tourtas, Schlötzer-Schrehardt, Kruse, Young, Quantock, Kinoshita, Koizumi: "Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 11, pp. 1291-304, (2015) (PubMed).

Details zu COL8a2

Target: COL8a2 (COL8A2) (Collagen, Type VIII, alpha 2 (COL8A2))

Andere Bezeichnung: COL8A2 (COL8A2 Produkte)

Synonyme: FECD antikoerper, FECD1 antikoerper, PPCD antikoerper, PPCD2 antikoerper, AI429819 antikoerper, collagen type VIII alpha 2 chain antikoerper, collagen, type VIII, alpha 2 antikoerper, COL8A2 antikoerper, Col8a2 antikoerper

Hintergrund: This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.

Molekulargewicht: 67244

Gen-ID: 1296

NCBI Accession: NP_005193

UniProt: P25067