ADAMTS18 Antikörper (C-Term)

Produktnummer ABIN652853

Produktdetails anti-ADAMTS18 Antikörper

Target: ADAMTS18 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18))

Bindungsspezifität: AA 1066-1095, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAMTS18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ADAMTS18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1066-1095 amino acids from the C-terminal region of human ADAMTS18.

Klon: RB22477

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-ADAMTS18 Antikörper (ABIN652853)

Reddy, Fernandes, Deshpande, Weisberg, Inguilizian, Abdel-Wahab, Kung, Levine, Griffin, Sattler: "The JAK2V617F oncogene requires expression of inducible phosphofructokinase/fructose-bisphosphatase 3 for cell growth and increased metabolic activity." in: Leukemia, Vol. 26, Issue 3, pp. 481-9, (2012) (PubMed).

Aldahmesh, Khan, Mohamed, Alkuraya, Ahmed, Bobis, Al-Mesfer, Alkuraya: "Identification of ADAMTS18 as a gene mutated in Knobloch syndrome." in: Journal of medical genetics, Vol. 48, Issue 9, pp. 597-601, (2011) (PubMed).

Details zu ADAMTS18

Target: ADAMTS18 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18))

Andere Bezeichnung: ADAMTS18 (ADAMTS18 Produkte)

Synonyme: 9630038L21 antikoerper, ADAMTS21 antikoerper, E130314N14Rik antikoerper, KNO2 antikoerper, RGD1560118 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 18 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 18 antikoerper, Adamts18 antikoerper, ADAMTS18 antikoerper

Hintergrund: ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor.

Molekulargewicht: 135167

Gen-ID: 170692

NCBI Accession: NP_955387

UniProt: Q8TE60