MC2R Antikörper (AA 261-288)

Produktnummer ABIN651731

Produktdetails anti-MC2R Antikörper

Target: MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))

Bindungsspezifität: AA 261-288

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MC2R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Pig

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MC2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids of human MC2R.

Klon: RB22805

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MC2R Antikörper (ABIN651731)

Tetsi Nomigni, Ouzounian, Benoit, Vadrot, Tissier, Renouf, Lefebvre, Christin-Maitre, Louiset: "Steroidogenic enzyme profile in an androgen-secreting adrenocortical oncocytoma associated with hirsustism." in: Endocrine connections, Vol. 4, Issue 2, pp. 117-27, (2015) (PubMed).

Details zu MC2R

Target: MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))

Andere Bezeichnung: MC2R (MC2R Produkte)

Synonyme: ACTHR antikoerper, ACTH-R antikoerper, MC2-R antikoerper, MC2R antikoerper, MC2 antikoerper, melanocortin 2 receptor antikoerper, MC2R antikoerper, Mc2r antikoerper, mc2r antikoerper

Hintergrund: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands.

Molekulargewicht: 33927

Gen-ID: 4158

NCBI Accession: NP_000520

UniProt: Q01718

Pathways: cAMP Metabolic Process