GLUT4 Antikörper
Kurzübersicht für GLUT4 Antikörper (ABIN636172)
Target
Alle GLUT4 (SLC2A4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität (Details)
- This mouse GT4 peptide sequence is 100 % conserved in rat, human, bovine, and pig Glut-4, 91 % in bovine. It has no significant sequence homology with other gluts.
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Aufreinigung
- Affinity chromatography purified
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Immunogen
- GLUT4 antibody was raised in rabbit using a 12 amino acid peptide from mouse Glut-4 as the immunogen.
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Isotyp
- IgG
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Applikationshinweise
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ELISA: 1:10,000, HC: 2-10 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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A synthetic GLUT4 Blocking peptide is available for validating specificity of this GLUT4 antibody, (ABIN935385)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in PBS to a concentration of 1 mg/mL.
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Konzentration
- Lot specific
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Buffer
- Lyophilized from PBS with 0.1 % BSA.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
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Andere Bezeichnung
- GLUT4
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Hintergrund
- Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Glut isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. Glut-4 (mouse/human 509-aa) is primarily expressed in muscle and adipose tissue and regulated by insulin.
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Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effekt
Target
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