Neurogranin Antikörper (Internal Region)

Produktnummer ABIN615919

Produktdetails anti-Neurogranin Antikörper

Target: Neurogranin (NRGN)

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Neurogranin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-KIKSGERGRK G

Spezifität: This antibody recognizes Neurogranin. Reported variants represent identical protein: NP_006167.1, NP_001119653.1

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog) and Bovine.
Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_006167.1. Genename: NRGN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Neurogranin

Target: Neurogranin (NRGN)

Andere Bezeichnung: Neurogranin (NRGN Produkte)

Synonyme: RC3 antikoerper, hng antikoerper, 0710001B06Rik antikoerper, AI838505 antikoerper, NG antikoerper, NG/RC3 antikoerper, Pss1 antikoerper, R75334 antikoerper, zgc:158686 antikoerper, neurogranin antikoerper, neurogranin (protein kinase C substrate, RC3) b antikoerper, NRGN antikoerper, Nrgn antikoerper, nrgnb antikoerper

Hintergrund: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.Synonyms: Ng, Nrgn, Protein kinase C substrate 7.5 kDa protein, RC3

Gen-ID: 4900

NCBI Accession: NP_006167

UniProt: Q92686