PCSK9 Antikörper (Internal Region)

Produktnummer ABIN569615

Produktdetails anti-PCSK9 Antikörper

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Bindungsspezifität: AA 164-175, Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PCSK9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-PRYRADEYQP PD

Spezifität: Recognizes PCSK9.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_777596.2.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PCSK9

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Andere Bezeichnung: PCSK9 (PCSK9 Produkte)

Synonyme: FH3 antikoerper, HCHOLA3 antikoerper, LDLCQ1 antikoerper, NARC-1 antikoerper, NARC1 antikoerper, PC9 antikoerper, AI415265 antikoerper, AI747682 antikoerper, Narc1 antikoerper, proprotein convertase subtilisin/kexin type 9 antikoerper, proprotein convertase subtilisin/kexin type 9 L homeolog antikoerper, PCSK9 antikoerper, pcsk9.L antikoerper, pcsk9 antikoerper, Pcsk9 antikoerper

Hintergrund: PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. PCSK9 may function as a proprotein convertase. PCSK9 plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in PCSK9 gene have been associated with a third form of autosomal dominant familial hypercholesterolemia.Synonyms: NARC-1, NARC1, Neural apoptosis-regulated convertase 1, PCSK-9, Proprotein convertase PC9, Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9

Gen-ID: 255738

NCBI Accession: NP_777596

UniProt: Q8NBP7