COX4I2
Reaktivität: Human
WB, IF, FACS
Wirt: Maus
Monoclonal
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1x PBS, pH 7.4
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Schiffer, Peleli, Sundqvist, Ekblom, Lundberg, Weitzberg, Larsen: "Control of human energy expenditure by cytochrome c oxidase subunit IV-2." in: American journal of physiology. Cell physiology, Vol. 311, Issue 3, pp. C452-61, (2016) (PubMed).
Aras, Pak, Sommer, Finley, Hüttemann, Weissmann, Grossman: "Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2." in: Nucleic acids research, Vol. 41, Issue 4, pp. 2255-66, (2013) (PubMed).
Hüttemann, Lee, Gao, Pecina, Pecinova, Liu, Aras, Sommer, Sanderson, Tost, Neff, Aguilar-Pimentel, Becker, Naton, Rathkolb, Rozman, Favor, Hans, Prehn, Puk, Schrewe, Sun, Höfler, Adamski, Bekeredjian et al.: "Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology. ..." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 9, pp. 3916-30, (2012) (PubMed).
Sundar Boyalla, Barbara Victor, Roemgens, Beyer, Arnold: "Sex- and brain region-specific role of cytochrome c oxidase in 1-methyl-4-phenylpyridinium-mediated astrocyte vulnerability." in: Journal of neuroscience research, Vol. 89, Issue 12, pp. 2068-82, (2011) (PubMed).
Singh, Misiak, Beyer, Arnold: "Brain region specificity of 3-nitropropionic acid-induced vulnerability of neurons involves cytochrome c oxidase." in: Neurochemistry international, Vol. 57, Issue 3, pp. 297-305, (2010) (PubMed).
Misiak, Singh, Drewlo, Beyer, Arnold: "Brain region-specific vulnerability of astrocytes in response to 3-nitropropionic acid is mediated by cytochrome c oxidase isoform expression." in: Cell and tissue research, Vol. 341, Issue 1, pp. 83-93, (2010) (PubMed).
Target
COX4I2
(Cytochrome C Oxidase Subunit IV Isoform 2 (Lung) (COX4I2))