Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1x PBS, pH 7.4
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Lekomtsev, Su, Pye, Blight, Sundaramoorthy, Takaki, Collinson, Cherepanov, Divecha, Petronczki: "Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis." in: Nature, Vol. 492, Issue 7428, pp. 276-9, (2012) (PubMed).
Wang, Ooi, Hui: "Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 18, pp. 6040-51, (2011) (PubMed).
Wolfe, Takaki, Petronczki, Glotzer: "Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation." in: PLoS biology, Vol. 7, Issue 5, pp. e1000110, (2009) (PubMed).
Burkard, Maciejowski, Rodriguez-Bravo, Repka, Lowery, Clauser, Zhang, Shokat, Carr, Yaffe, Jallepalli: "Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells." in: PLoS biology, Vol. 7, Issue 5, pp. e1000111, (2009) (PubMed).
Target
RACGAP1
(Rac GTPase Activating Protein 1 (RACGAP1))