CPB6 antikoerper, CYP2B antikoerper, CYP2B7 antikoerper, CYP2B7P antikoerper, CYPIIB6 antikoerper, EFVM antikoerper, IIB1 antikoerper, P450 antikoerper, CPF3 antikoerper, CYP4F antikoerper, LTB4H antikoerper, CYP2B30 antikoerper, CYP2B11 antikoerper, CYPIIB11 antikoerper, 21-OH antikoerper, 21OH antikoerper, 21OHA antikoerper, 21OHB antikoerper, CYP21OH-A antikoerper, Cyp21 antikoerper, Cyp21-ps1 antikoerper, Cyp21B antikoerper, Cyp21a2-ps antikoerper, Cyp21a2ps antikoerper, Oh21-1 antikoerper, Oh21-2 antikoerper, CYP2B6 antikoerper, cytochrome P450 family 2 subfamily B member 6 antikoerper, cytochrome P450 family 4 subfamily F member 3 antikoerper, cytochrome P450, family 2, subfamily B, polypeptide 6 antikoerper, cytochrome P450 family 2 subfamily B member 6 L homeolog antikoerper, cytochrome P450 2B11 antikoerper, cytochrome P450, family 21, subfamily a, polypeptide 1 antikoerper, cytochrome P450 subfamily 2B antikoerper, cytochrome P450 2B11-like antikoerper, CYP2B6 antikoerper, CYP4F3 antikoerper, cyp2b6.L antikoerper, Cyp21a1 antikoerper, LOC100068603 antikoerper
Hintergrund
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described, however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.Synonyms: CYPIIB6, Cytochrome P450 2B6, Cytochrome P450 IIB1