Importin 8 Antikörper (C-Term)

Produktnummer ABIN954450

Produktdetails anti-Importin 8 Antikörper

Target: Importin 8 (IPO8)

Bindungsspezifität: C-Term

Reaktivität: Human, Hund, Rind (Kuh), Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Importin 8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-SAFNFGTVPS NN

Spezifität: This antibody is expected to recognise isoform 1 (NP_006381.2) and isoform 2 (NP_001177924.1).

Kreuzreaktivität (Details): Species reactivity (expected):Dog, Pig, Cow.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C-Terminus of the protein sequence according to NP_006381.2, NP_001177924.1. Genename: IPO8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Importin 8

Target: Importin 8 (IPO8)

Andere Bezeichnung: RanBP8 / Importin-8 (IPO8 Produkte)

Synonyme: IPO8 antikoerper, si:ch211-116i17.1 antikoerper, RANBP8 antikoerper, 6230418K12Rik antikoerper, Abcc10 antikoerper, C130009K11Rik antikoerper, MRP7 antikoerper, OM-1 antikoerper, Om1 antikoerper, Ranbp8 antikoerper, importin 8 antikoerper, IPO8 antikoerper, ipo8 antikoerper, Ipo8 antikoerper

Hintergrund: Importin 8 is a 1037 amino acid nuclear protein with a RAN binding site. It belongs to RAN-binding protein super family and hence shares an N-terminal sequence motif with importin-beta that appears to account for RAN GTP binding. It binds to the nuclear pore complex (NPC) and is well known as a transport carrier that mediates nuclear import of ribosomal proteins with a classical nuclear localization signal. Importin 8 works by binding to the nuclear pore complex and, along with RANGTP and RANBP1, inhibits the GAP stimulation of the RAN GTPase. Along with transportin it also helps in the nuclear import of SRP19.Synonyms: IMP8, IPO8, RAN binding protein 8

Gen-ID: 10526

NCBI Accession: NP_006381