ERAP2 Antikörper (Internal Region)

Produktnummer ABIN374998

Produktdetails anti-ERAP2 Antikörper

Target: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ERAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to ERAP2.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-QYLKKFSYRNAKND, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ERAP2

Target: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Andere Bezeichnung: ERAP2 / LRAP (ERAP2 Produkte)

Synonyme: L-RAP antikoerper, LRAP antikoerper, ERAP2 antikoerper, zgc:172163 antikoerper, endoplasmic reticulum aminopeptidase 2 antikoerper, ERAP2 antikoerper, erap2 antikoerper

Hintergrund: ERAP2 is an aminopeptidase that plays a central role in peptide trimming. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP2 to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II. ERAP2 preferentially hydrolyzes the basic residues Arg and Lys.Synonyms: Endoplasmic reticulum aminopeptidase 2, L-RAP, Leukocyte-derived arginine aminopeptidase

Gen-ID: 64167

NCBI Accession: NP_001123612

UniProt: Q6P179