Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (Internal Region) Antikörper

Details zu Produkt Nr. ABIN5553286, Anbieter: Anmelden zum Anzeigen
Antigen
  • p40phox
  • AI451400
  • NCF
  • P40PHOX
  • SH3PXD4
  • p40phox protein
  • neutrophil cytosolic factor 4
  • neutrophil cytosolic factor 4, 40kDa
  • p40phox
  • LOC100136241
  • Ncf4
  • NCF4
Epitop
Internal Region
19
9
8
4
4
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Hund, Human
117
58
44
7
6
5
4
4
3
3
Wirt
Ziege
91
19
11
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
74
41
33
26
22
5
4
3
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Peptide with sequence C-KDFPEEDDPTN, from the internal region of the protein sequence
Spezifität This antibody reacts to NCF4 / P40PHOX.
Kreuzreaktivität (Details) Species reactivity (expected):Canine.
Species reactivity (tested):Human.
Reinigung Affinity chromatography
Andere Bezeichnung NCF-4 (NCF4 Antibody Abstract)
Hintergrund NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.Synonyms: Neutrophil NADPH oxidase factor 4, Neutrophil cytosol factor 4, SH3 and PX domain-containing protein 4, SH3PXD4, p40-phox
Gen-ID 4689
NCBI Accession NP_000622
UniProt Q15080
Applikationshinweise Peptide ELISA: 1/32000. Western blot: Approx.38 kDa band observed in lysates of cell line Daudi (calculated MW of39.8 kDa according to NP_000622.2 and 38.8 kDa according to NP_038202.1). Intransfected HEK293 transiently expressing P40PHOX a band of approx.48 kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.3 - 1 μg/mL. Immunohistochemistry on paraffin sections: Human Tonsil shows staining of thecytoplasm in some cells. Recommended concentration: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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