VDAC2 Antikörper (C-Term)
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- Target Alle VDAC2 Antikörper anzeigen
- VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte, Maus, Hund, Rind (Kuh), Schwein
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser VDAC2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequenz
- C-GHKVGLALEL EA
- Spezifität
- This antibody detects VDAC-2 at C-term.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Canine (Dog), Bovine and Pig.
Species reactivity (tested):Human, Rat. - Aufreinigung
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- Immunogen
- Peptide from C-Terminus of the protein sequence according to NP_003366.2 Genename: VDAC2
- Top Product
- Discover our top product VDAC2 Primärantikörper
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- Applikationshinweise
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Peptide ELISA: Antibody Limit dilution 1/64000. Western blot: 0.3-1.0 μg/mL. Approx 30 kDa band observed in Human Brain and HumanTestis lysates (calculated MW of 31.0 kDa according to NP_003366.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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Relationship of sperm small heat-shock protein 10 and voltage-dependent anion channel 2 with semen freezability in boars." in: Theriogenology, Vol. 82, Issue 3, pp. 418-26, (2014) (PubMed).
: "Expression and activity of alcohol and aldehyde dehydrogenases in melanoma cells and in melanocytes." in: Journal of cellular biochemistry, Vol. 113, Issue 3, pp. 792-9, (2012) (PubMed).
: "Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 10, pp. 3570-82, (2011) (PubMed).
: "BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution." in: Journal of neurochemistry, Vol. 111, Issue 3, pp. 801-7, (2009) (PubMed).
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Relationship of sperm small heat-shock protein 10 and voltage-dependent anion channel 2 with semen freezability in boars." in: Theriogenology, Vol. 82, Issue 3, pp. 418-26, (2014) (PubMed).
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- Target
- VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))
- Andere Bezeichnung
- VDAC2 (VDAC2 Produkte)
- Synonyme
- POR antikoerper, Vdac6 antikoerper, mVDAC2 antikoerper, mVDAC6 antikoerper, wu:fa01a08 antikoerper, wu:fa98a10 antikoerper, wu:fb50g11 antikoerper, zgc:55795 antikoerper, zgc:77621 antikoerper, vdac2 antikoerper, VDAC2 antikoerper, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2 antikoerper, ATVDAC2 antikoerper, K9I9.6 antikoerper, K9I9_6 antikoerper, voltage dependent anion channel 2 antikoerper, voltage dependent anion channel 2 antikoerper, voltage-dependent anion channel 2 antikoerper, voltage-dependent anion channel 2 S homeolog antikoerper, VDAC2 antikoerper, Vdac2 antikoerper, vdac2 antikoerper, vdac2.S antikoerper
- Hintergrund
- VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. VDAC2 interacts with hexokinases. It is present in the outer mitochondrial membrane. There are 4 isoforms as result of alternative splicing. It consists mainly of membrane spanning sided beta sheets, and belongs to the eukaryotic mitochondrial porin family.Synonyms: Outer mitochondrial membrane protein porin 2, VDAC-2, Voltage-dependent anion-selective channel protein 2
- Gen-ID
- 7417
- NCBI Accession
- NP_003366
- UniProt
- P45880
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