IQCB1 Antikörper

Produktnummer ABIN498968

Produktdetails anti-IQCB1 Antikörper

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IQCB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Nephrocystin-5 protein. (region surrounding Arg467)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Andere Bezeichnung: IQCB1 (IQCB1 Produkte)

Synonyme: piq antikoerper, nphp5 antikoerper, slsn5 antikoerper, MGC81507 antikoerper, IQCB1 antikoerper, zgc:101792 antikoerper, MGC146213 antikoerper, 6820449I09Rik antikoerper, AV128382 antikoerper, NPHP5 antikoerper, PIQ antikoerper, SLSN5 antikoerper, IQ motif containing B1 antikoerper, IQ motif containing B1 L homeolog antikoerper, IQ calmodulin-binding motif containing 1 antikoerper, Iqcb1 antikoerper, iqcb1.L antikoerper, IQCB1 antikoerper, iqcb1 antikoerper

Hintergrund: CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells, may play a role in ciliary transport processes. CEP290 is ubiquitously expressed, strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5) [MIM:610188], Senior-Loken syndrome type 6 (SLSN6) [MIM:610189], Leber congenital amaurosis type 10 (LCA10) [MIM:611755] and Meckel syndrome type 4 (MKS4) [MIM:611134]. Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.Synonyms: IQ calmodulin-binding motif-containing protein 1, KIAA0036, NPHP5, OK/SW-cl.85

Molekulargewicht: approx. 69 kDa

Gen-ID: 9657

NCBI Accession: NP_001018864

UniProt: Q15051