PF4 Antikörper (AA 30-105)

Produktnummer ABIN4886693

Produktdetails anti-PF4 Antikörper

Target: PF4 (Platelet Factor 4 (PF4))

Bindungsspezifität: AA 30-105

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Platelet factor 4(PF4) detection. Tested with WB, IHC-P, ELISA in Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Platelet factor 4(PF4) detection. Tested with WB, IHC-P, ELISA in Mouse,Rat.
Gene Name: platelet factor 4
Protein Name: Platelet factor 4

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse PF4 recombinant protein (Position: V30-S105). Mouse PF4 shares 74.3% and 86.8% amino acid (aa) sequence identity with human and rat PF4, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu PF4

Target: PF4 (Platelet Factor 4 (PF4))

Andere Bezeichnung: PF4 (PF4 Produkte)

Synonyme: CXCL4 antikoerper, PF-4 antikoerper, SCYB4 antikoerper, Cxcl4 antikoerper, Scyb4 antikoerper, Pf4a antikoerper, RATPF4A antikoerper, PF4A antikoerper, CXCL4L1 antikoerper, CXCL4V1 antikoerper, PF4-ALT antikoerper, SCYB4V1 antikoerper, PF4 antikoerper, platelet factor 4 antikoerper, platelet factor 4 variant 1 antikoerper, PF4 antikoerper, Pf4 antikoerper, LOC703451 antikoerper, PF4V1 antikoerper, LOC100524373 antikoerper, LOC102181854 antikoerper, LOC100630489 antikoerper

Hintergrund: Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

Synonyms: Platelet factor 4(PF4) | Platelet factor 4(PF-4) | platelet factor4 | CXCL4 | Iroplact | OncostatinA | Oncostatin-A | PF4 | PF-4 | PLF4 | SCYB 4 | SCYB4 | P02776

Gen-ID: 56744

UniProt: Q9Z126