p21 Antikörper (pThr145)
Kurzübersicht für p21 Antikörper (pThr145) (ABIN482541)
Target
Alle p21 (CDKN1A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 111-160, pThr145
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Spezifität
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p21 Cip1 (Phospho-Thr145) Antibody detects endogenous levels of p21 Cip1 only when phosphorylated at Thr145.
PhosphorylationH:T145 M:T140 R:T145
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human p21 Cip1 around the phosphorylation site of Thr145.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
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Kommentare
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Unigene-Number: Hs.370771 (NCBI Gene Symbol: CDKN1A)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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- p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
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Andere Bezeichnung
- p21 Cip1
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Hintergrund
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Synonyms: CAP20, CDK-interacting protein 1, CDKN1, CDKN1A, CDN1A, CIP1, Cyclin-dependent kinase inhibitor 1, MDA-6, MDA6, Melanoma differentiation associated protein, Melanoma differentiation associated protein 6, p21, PIC1, SDI1, WAF1
NCBI Gene Symbol: CDKN1A
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Molekulargewicht
- 17 kDa
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Gen-ID
- 1026
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OMIM
- 116899
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UniProt
- P38936
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagie
Target
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