RPS6KB1 Antikörper (pThr412)
Kurzübersicht für RPS6KB1 Antikörper (pThr412) (ABIN481970)
Target
Alle RPS6KB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 355-404, pThr412
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Spezifität
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p70 S6 Kinase (Phospho-Thr389) Antibody detects endogenous levels of p70 S6 Kinase only when phosphorylated at Thr389.
PhosphorylationH:T412 M:T412 R:T412
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Thr389.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000
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Kommentare
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Unigene-Number: Hs.463642 (NCBI Gene Symbol: RPS6KB1)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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: "Fibrous papule of the face, similar to tuberous sclerosis complex-associated angiofibroma, shows activation of the mammalian target of rapamycin pathway: evidence for a novel therapeutic strategy?" in: PLoS ONE, Vol. 9, Issue 2, pp. e89467, (2014) (PubMed).
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- RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
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Andere Bezeichnung
- p70 S6 Kinase
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Hintergrund
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Synonyms: Ribosomal protein S6 kinase I, S6K, S6K1, 70 kDa ribosomal protein S6 kinase 1, p70 S6 kinase alpha, p70(S6K)-alpha, p70-S6K, P70S6K, p70-alpha
NCBI Gene Symbol: RPS6KB1
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Molekulargewicht
- 59 kDa
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Gen-ID
- 6198
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OMIM
- 608938
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UniProt
- P23443
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Pathways
- PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effekt
Target
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