COL4A3BP Antikörper

Produktnummer ABIN4620375

Produktdetails anti-COL4A3BP Antikörper

Target: COL4A3BP (Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL4A3BP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects CERTL.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide derived from human CERTL protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot (1: 400 starting dilution). Positive control: Ovary.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Details zu COL4A3BP

Target: COL4A3BP (Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP))

Andere Bezeichnung: COL4A3BP (COL4A3BP Produkte)

Synonyme: COL4A3BP antikoerper, 2810404O15Rik antikoerper, 9230101K08Rik antikoerper, AU016711 antikoerper, CERT antikoerper, GPBP antikoerper, col4a3bp antikoerper, wu:fc37f11 antikoerper, zgc:92147 antikoerper, CERTL antikoerper, STARD11 antikoerper, cert antikoerper, certl antikoerper, cetp antikoerper, gpbp antikoerper, stard11 antikoerper, collagen type IV alpha 3 binding protein antikoerper, collagen, type IV, alpha 3 (Goodpasture antigen) binding protein antikoerper, collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a antikoerper, collagen, type IV, alpha 3 (Goodpasture antigen) binding protein L homeolog antikoerper, COL4A3BP antikoerper, Col4a3bp antikoerper, col4a3bpa antikoerper, col4a3bp.L antikoerper

Hintergrund: CERT mediates the ATP-dependent ER-to-Golgi transfer of ceramide in a non-vesicular manner. The biosynthesis of lipids involves steps that occur in different intracellular compartments. The movement of lipids within these compartments is important in lipid-mediated signalling. Human CERT is identical to a splice variant of human Goodpasture antigen-binding protein (GPBP26). CERT contains a phosphoinositide-binding pleckstrin-homology (PH) domain (which targets CERT to the Golgi by binding phosphatidylinositol-4-phosphate (PtdIns4P)), a middle region, and a putative lipid-transfer-catalysing domain called START. CERT and CERTL can specifically extract ceramide from phospholipid bilayers in a START-domain-dependent manner. CERT interacts with ER membranes and specifically extracts ceramide. CERT catalyses both the specific extraction of ceramide from donor vesicles and its transfer to acceptor vesicles. CERT can associate with the Golgi in a PtdIns4P dependent manner.Synonyms: CERT, Ceramide transfer protein, Collagen type IV alpha-3-binding protein, GPBP, Goodpasture antigen-binding protein, STARD11, START domain-containing protein 11, StAR-related lipid transfer protein 11, StARD11, hCERT

Gen-ID: 10087

NCBI Accession: NP_001123577

UniProt: Q9Y5P4