SRSF2 Antikörper (Middle Region)
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- Target Alle SRSF2 Antikörper anzeigen
- SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))
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Bindungsspezifität
- AA 83-113, Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SRSF2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody reacts to SFRS2.
- Aufreinigung
- Saturated Ammonium Sulfate (SAS) precipitation
- Immunogen
- KLH conjugated synthetic peptide selected from aa 83-113 from the Center region of human SFRS2
- Top Product
- Discover our top product SRSF2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))
- Andere Bezeichnung
- SFRS2 / SC-35 (SRSF2 Produkte)
- Synonyme
- PR264 antikoerper, SC-35 antikoerper, SC35 antikoerper, SFRS2 antikoerper, SFRS2A antikoerper, SRp30b antikoerper, D11Wsu175e antikoerper, MRF-1 antikoerper, Pr264 antikoerper, Sfrs10 antikoerper, Sfrs2 antikoerper, pr264 antikoerper, sc-35 antikoerper, sc35 antikoerper, sfrs2 antikoerper, sfrs2a antikoerper, srp30b antikoerper, serine and arginine rich splicing factor 2 antikoerper, serine/arginine-rich splicing factor 2 antikoerper, serine/arginine-rich splicing factor 2 L homeolog antikoerper, SRSF2 antikoerper, Srsf2 antikoerper, srsf2.L antikoerper
- Hintergrund
- SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway.Synonyms: Nuclear Speckle Marker, PR264, Splicing component 35 kDa, Splicing factor SC35, Splicing factor arginine/serine-rich 2
- Gen-ID
- 6427
- NCBI Accession
- NP_003007
- UniProt
- Q01130
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