CYP2C19 Antikörper (Middle Region)

Produktnummer ABIN452898

Produktdetails anti-CYP2C19 Antikörper

Target: CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP2C19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects CYP2C19 at Center.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CYP2C19

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu CYP2C19

Target: CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))

Andere Bezeichnung: CYP2C19 (CYP2C19 Produkte)

Synonyme: CPCJ antikoerper, CYP2C antikoerper, P450C2C antikoerper, P450IIC19 antikoerper, cytochrome P450 family 2 subfamily C member 19 antikoerper, cytochrome P450, family 2, subfamily C, polypeptide 19 antikoerper, cytochrome P450 2C19 antikoerper, CYP2C19 antikoerper

Hintergrund: CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.Synonyms: (R)-limonene 6-monooxygenase, CYPIIC17, CYPIIC19, Cytochrome P450 2C19, Cytochrome P450-254C, Mephenytoin 4-hydroxylase

Molekulargewicht: 55931 Da

Gen-ID: 1557

NCBI Accession: NP_000760

UniProt: P33261