Antibody AP09476PU detects endogenous levels of GAP43 only when phosphorylated at Ser41.
Aufreinigung
Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human GAP43 around the phosphorylation site of Ser41 (Q-A-Sp-F-R).
Immunofluorescence: 1/100approx. 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
B-50 antikoerper, PP46 antikoerper, Basp2 antikoerper, GAP-43 antikoerper, b-50 antikoerper, gap-43 antikoerper, gap43b antikoerper, pp46 antikoerper, cb310 antikoerper, gap antikoerper, gap43 antikoerper, gap43a antikoerper, growth associated protein 43 antikoerper, growth associated protein 43 L homeolog antikoerper, growth associated protein 43 S homeolog antikoerper, GAP43 antikoerper, Gap43 antikoerper, gap43.L antikoerper, gap43 antikoerper, gap43.S antikoerper
Hintergrund
GAP43 is expressed by developing and regenerating neurons, and to a lesser extent, reactive glial cells. It is used widely to specifically label injured neurons and to score neuronal regeneration. GAP43 is also a neuronal growth cone protein thought to be involved in pathfinding.Synonyms: Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46