Angiotensin I Converting Enzyme 1 Antikörper

Produktnummer ABIN379980

Der Maus Monoklonal anti-Angiotensin I Converting Enzyme 1 Antikörper (Klon CG2) (ABIN379980) detektiert spezifisch Angiotensin I Converting Enzyme 1 in IHC und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Angiotensin I Converting Enzyme 1 Antikörper (ABIN379980)

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Angiotensin I Converting Enzyme 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CG2

Produktdetails anti-Angiotensin I Converting Enzyme 1 Antikörper

Spezifität: The antigen is CD143, the epitope is apparently localized in the N-terminal portion of the protein. Antigen distribution: Tissue sections: Topographically the degree of expression correlates with the proportion of smooth muscle cells and elastic fibres of the vessel wall. ACE is predominantely expressed by small muscular arteries and by arterioles, whereas small and large veins do not usually express ACE. However, no ACE could be detected in the endothelial cells of kidney. Constitutively ACE is expressed on endothelial cells in different diseases like hypertension, myocardial infarction, sarcoidosis, diabetes. Specificity: Human: denatured ACE. Other species: not tested.

Aufreinigung: Affinity purified

Immunogen: purified ACE from human lung and kidney

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (1:50)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.1 % Kathon

Konservierungsmittel: Kathon CG

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu Angiotensin I Converting Enzyme 1

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Andere Bezeichnung: ACE / DCP1 / CD143

Hintergrund: Name/Gene ID: ACE
Subfamily: Metallopeptidase M2
Family: Protease

Synonyms: ACE, ACE1, Angiotensin-converting enzyme, CD143, CD143 antigen, Carboxycathepsin, DIPEPTIDYL CARBOXYPEPTIDASE, DCP, Dipeptidyl carboxypeptidase I, ICH, Kininase II, MVCD3, Peptidyl-dipeptidase A, Peptidase P, DCP1, Dipeptidyl carboxypeptidase 1, Testicular ECA

Gen-ID: 1636

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration