Biglycan Antikörper (C-Term)
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- Target Alle Biglycan (BGN) Antikörper anzeigen
- Biglycan (BGN)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte, Maus, Hund
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Biglycan Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Sequenz
- C-DRLAIQFGNY KK
- Spezifität
- This antibody recognizes Biglycan Preproprotein.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human, Rat. - Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- Immunogen
- Synthetic peptide from the C-Terminus of Human Biglycan (NP_001702.1) Genename: BGN
- Top Product
- Discover our top product BGN Primärantikörper
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- Applikationshinweise
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Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Biglycan (BGN)
- Andere Bezeichnung
- Biglycan (BGN Produkte)
- Synonyme
- DSPG1 antikoerper, PG-S1 antikoerper, PGI antikoerper, SLRR1A antikoerper, BG antikoerper, BSPG1 antikoerper, bgn antikoerper, zgc:91989 antikoerper, dspg1 antikoerper, pg-s1 antikoerper, slrr1a antikoerper, xbgn antikoerper, BGN antikoerper, zgc:77123 antikoerper, DKFZp468I2427 antikoerper, biglycan antikoerper, biglycan L homeolog antikoerper, biglycan a antikoerper, biglycan S homeolog antikoerper, biglycan b antikoerper, BGN antikoerper, Bgn antikoerper, bgn.L antikoerper, bgna antikoerper, bgn.S antikoerper, bgn antikoerper, bgnb antikoerper
- Hintergrund
- Biglycan is an extracellular matrix proteoglycan that is closely related in structure to decorin and fibromodulin. Biglycan and decorin are thought to be the result of a gene duplication. Biglycan is expressed in secondary myotubes during fetal muscle formation. In adult muscle it is located in the endomysium and neuromuscular junctions, where it connects to the dystrophin-associated proteins through binding to a-dystroglycan. In developing newborn mice biglycan expression is initially high and then decreases during skeletal muscle differentiation and maturation. Biglycan may also have a role in the fibrotic process since it is overexpressed in atherosclerotic lesions and has been shown to cause an increase in thymidine incorporation and migration of vascular smooth muscle cells.Synonyms: BGN, Bone/cartilage proteoglycan I, PG-S1, PGS1, SLRR1A, Small Leucine-rich Protein 1A
- Molekulargewicht
- 41.7 kDa (Human NP_001702.1 and Rat NP_058783.1)
- Gen-ID
- 633
- NCBI Accession
- NP_001702
- UniProt
- P21810
- Pathways
- Glycosaminoglycan Metabolic Process
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