HSD17B10 Antikörper (C-Term)

Produktnummer ABIN374505

Produktdetails anti-HSD17B10 Antikörper

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Affe, Hund, Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser HSD17B10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to HSD17B10.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence CIRLDGAIRMQP, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.3 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HSD17B10

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Andere Bezeichnung: HSD17B10 / ERAB (HSD17B10 Produkte)

Synonyme: hadh2 antikoerper, im:6899159 antikoerper, wu:fj61f03 antikoerper, zgc:101605 antikoerper, abad antikoerper, camr antikoerper, erab antikoerper, hcd2 antikoerper, hsd10 antikoerper, mhbd antikoerper, mrpp2 antikoerper, mrx17 antikoerper, mrx31 antikoerper, mrxs10 antikoerper, schad antikoerper, sdr5c1 antikoerper, HADH2 antikoerper, HSD17B10 antikoerper, 17b-HSD10 antikoerper, ABAD antikoerper, CAMR antikoerper, DUPXp11.22 antikoerper, ERAB antikoerper, HCD2 antikoerper, MHBD antikoerper, MRPP2 antikoerper, MRX17 antikoerper, MRX31 antikoerper, MRXS10 antikoerper, SCHAD antikoerper, SDR5C1 antikoerper, 17bHSD10 antikoerper, Ads9 antikoerper, Hadh2 antikoerper, hydroxysteroid (17-beta) dehydrogenase 10 antikoerper, hydroxysteroid 17-beta dehydrogenase 10 antikoerper, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog antikoerper, HSD17B10 antikoerper, hsd17b10 antikoerper, hsd17b10.L antikoerper, Hsd17b10 antikoerper

Hintergrund: ERAB is a member of the short-chain dehydrogenase/reductase superfamily. This mitochondrial protein catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. It has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD, a disorder characterized by neurological abnormalities, including psychomotor retardation and loss of mental and motor skills). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. Abundant in human liver, kidney and gonads, but it is present in only negligible amounts in skeletal muscle. At the sub-cellular level, in normal tissues, this protein is located in mithocondria. It is over-expressed in Neurons of patients with Alzheimer's disease.Synonyms: 17-beta-HSD10, 17-beta-hydroxysteroid dehydrogenase 10, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, 3-hydroxyacyl-CoA dehydrogenase type-2, Endoplasmic reticulum-associated amyloid beta-peptide-binding protein, HADH2, MRPP2, Mitochondrial Marker, Mitochondrial ribonuclease P protein 2, SCHAD, Short-chain type dehydrogenase/reductase XH98G2, Type II HADH, XH98G2

Gen-ID: 3028, 9606

UniProt: Q99714