RDH11 Antikörper (C-Term, N-Term)

Produktnummer ABIN372579

Produktdetails anti-RDH11 Antikörper

Target: RDH11 (Retinol Dehydrogenase 11 (All-Trans/9-Cis/11-Cis) (RDH11))

Bindungsspezifität: AA 1-7, C-Term, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RDH11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Recognizes Retinol Dehydrogenase 11 (all-trans/9-cis/11-cis) (RDH11).
Cellular Localization: Endoplasmic reticulum membrane, Single-pass type II membrane protein.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated corresponding to N-terminal sequence MVELMFP (aa 1-7) and the C-terminal sequence LLGLPID (312-318) of the Human RDH11.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu RDH11

Target: RDH11 (Retinol Dehydrogenase 11 (All-Trans/9-Cis/11-Cis) (RDH11))

Andere Bezeichnung: RDH11 (RDH11 Produkte)

Synonyme: RDH11 antikoerper, 2610319N22Rik antikoerper, AI428145 antikoerper, AU045252 antikoerper, Arsdr1 antikoerper, C85936 antikoerper, CGI-82 antikoerper, HCBP12 antikoerper, M42C60 antikoerper, Mdt1 antikoerper, Psdr1 antikoerper, SCALD antikoerper, UBE-1c1 antikoerper, Ube-1c antikoerper, ARSDR1 antikoerper, CGI82 antikoerper, MDT1 antikoerper, PSDR1 antikoerper, RALR1 antikoerper, SDR7C1 antikoerper, retinol dehydrogenase 11 (all-trans/9-cis/11-cis) S homeolog antikoerper, retinol dehydrogenase 11 (all-trans/9-cis/11-cis) antikoerper, retinol dehydrogenase 11 antikoerper, rdh11.S antikoerper, RDH11 antikoerper, Rdh11 antikoerper

Hintergrund: RDH11 (Retinol dehydrogenase 11) exhibits an oxidoreductive catalytic activity towards retinoids. RDH11 is most efficient as an NADPH-dependent all-trans-retinal reductase. RDH11 is also involved in the metabolism of short-chain aldehydes. RDH11 is located in endoplasmic reticulum and is expressed at higher level in liver and testis and is expressed at lower levels in smooth muscle, thymus, submaxillary gland and epididymis. In testis, expression is restricted to pachytene spermatocytes. RDH11 is also expressed in four layers of the retina, including the outer segment of rods and cones. RDH11 belongs to the short-chain dehydrogenases/reductases (SDR) family.Synonyms: ARSDR1, CGI-82, HCBP12, HCV core-binding protein HCBP12, PSDR1, Prostate short-chain dehydrogenase/reductase 1, RalR1, Retinal Reductase 1, Retinol Dehydrogenase 11

Molekulargewicht: 35 kDa

Gen-ID: 51109

NCBI Accession: NP_057110

UniProt: Q8TC12