HAVCR1 Antikörper (Hepatitis A Virus Cellular Receptor 1) (AA 200-300)

Details for Product anti-HAVCR1 Antibody No. ABIN372415, Anbieter: Anmelden zum Anzeigen
Antigen
  • HAVCR1
  • LOC100226241
  • AI503787
  • KIM-1
  • TIM-1
  • Tim1
  • Timd1
  • HAVCR
  • HAVCR-1
  • KIM1
  • TIM
  • TIM1
  • TIMD-1
  • TIMD1
  • Kim1
  • hepatitis A virus cellular receptor 1
  • Rho guanine nucleotide exchange factor (GEF) 5
  • RCJMB04_10h2
  • HAVCR1
  • LOC100226241
  • Havcr1
  • Arhgef5
Epitop
AA 200-300
18
15
9
8
8
7
7
6
6
6
6
5
5
5
5
5
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus
104
43
26
11
6
1
1
1
Wirt
Kaninchen
108
47
9
5
Klonalität
Polyklonal
Konjugat
Dieser HAVCR1 Antikörper ist unkonjugiert
13
11
6
5
4
3
2
2
2
2
2
2
2
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
114
91
30
21
20
11
8
5
4
4
4
2
2
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen Synthetic peptide corresponding amino acids 200-300 of human HAVCR1.
Isotyp IgG
Spezifität This antibody recognizes Hepatitis A Virus Cellular Receptor 1 (HAVCR1).
Kreuzreaktivität (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Reinigung Protein G Chromatography.
Andere Bezeichnung TIMD1 / HAVCR1 (HAVCR1 Antibody Abstract)
Hintergrund HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epithelium in Kidneys. HAVCR1 has shown to be upregulated in renal carcinomas, suggesting its role in tumor progression and metastasis.Synonyms: HAVCR-1, Hepatitis A virus cellular receptor 1, T cell immunoglobulin and mucin domain-containing protein 1, T cell membrane protein 1, TIM-1, TIM1, TIMD-1
Gen-ID 26762
NCBI Accession NP_001092884
UniProt Q96D42
Applikationshinweise Immunohistochemistry on Paraffin Sections: 2.5-5.0 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.5 mg/mL
Buffer PBS containing 0.05 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Bilder des Herstellers
 image for anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 200-300) antibody (ABIN372415) anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 200-300) antibody
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