IL4 Receptor Antikörper (Extracellular Domain)
Kurzübersicht für IL4 Receptor Antikörper (Extracellular Domain) (ABIN360908)
Target
Alle IL4 Receptor (IL4R) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- Extracellular Domain
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Spezifität
- This antibody detects IL-4R.
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Aufreinigung
- Protein A/G affinity chromatography
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Immunogen
- Recombinant protein of IL-4R extracellular domain.
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Isotyp
- IgG2
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Applikationshinweise
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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Andere Bezeichnung
- CD124 / IL4R
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Hintergrund
- The Interleukin-4 receptor is a complex consisting of two chains. One chain is the high affinity IL-4 binding (p140, a chain, CD 124) chain and the other chain is the gamma chain. The high affinity IL-4 binding chain belongs to the cytokine receptor superfamily. The cytoplasmic domain contains Ser/Pro-rich regions similar to those present in the IL-2 receptor and GM-CSF receptor ß-chains. The recombinant human IL-4 soluble receptor corresponds to the human IL-4 receptor extracellular domain. The recombinant, human IL-4 sR is a potent IL-4 antagonist. This antibody will block IL-4 binding to its receptor.Synonyms: 582J2.1, IL-4R-alpha, IL4 Receptor alpha, IL4RA, Interleukin-4 receptor alpha chain
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Gen-ID
- 16190
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NCBI Accession
- NP_001008700
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UniProt
- P16382
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Pathways
- JAK-STAT Signalweg, Positive Regulation of Immune Effector Process
Target
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