ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
ACVR2 antikoerper, ACVR2A antikoerper, XSTK9 antikoerper, actrii antikoerper, acvr2 antikoerper, ACTRII antikoerper, Acvr2 antikoerper, rActR-II antikoerper, actr2a antikoerper, acvr2a antikoerper, wu:fa02e10 antikoerper, ActrIIa antikoerper, TactrII antikoerper, activin A receptor type 2A antikoerper, activin A receptor type 2A L homeolog antikoerper, activin A receptor type 2Aa antikoerper, activin receptor IIA antikoerper, ACVR2A antikoerper, acvr2a antikoerper, Acvr2a antikoerper, acvr2a.L antikoerper, acvr2aa antikoerper
Hintergrund
ACVR2A is an activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.Synonyms: ACTR-IIA, ACTRIIA, Activin A receptor type IIA