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LST1 Antikörper

LST1 Reaktivität: Human WB, IP, ICC Wirt: Maus Monoclonal LST1-02 unconjugated
Produktnummer ABIN343705
  • Target Alle LST1 Antikörper anzeigen
    LST1 (Leukocyte Specific Transcript 1 (LST1))
    Reaktivität
    Human
    Wirt
    • 30
    • 4
    Maus
    Klonalität
    • 31
    • 3
    Monoklonal
    Konjugat
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LST1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Spezifität
    The antibody LST1/02 reacts with an extracellular epitope of LST1, an approximately 6-11 kDa protein expressed as various transmembrane or soluble forms. LST1 is found predominantly on monocytes and dendritic cells. It migrates on SDS PAGE gels as approximately 25-28 kDa molecule.
    Kreuzreaktivität (Details)
    Human, Other not determined
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    KLH-fused peptide corresponding to amino acids SSEGPDLRGRDKRGT of human LST1
    Klon
    LST1-02
    Isotyp
    IgG1
    Top Product
    Discover our top product LST1 Primärantikörper
  • Applikationshinweise
    Immunoprecipitation: Positive control: RAJI human Burkitt lymphoma cell line.
    Western blotting: The antigen migrates on SDS PAGE gels as approximately 25-28 kDa molecule.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    LST1 (Leukocyte Specific Transcript 1 (LST1))
    Andere Bezeichnung
    LST1 (LST1 Produkte)
    Synonyme
    B144 antikoerper, D6S49E antikoerper, LST-1 antikoerper, leukocyte specific transcript 1 antikoerper, LST1 antikoerper, Lst1 antikoerper
    Hintergrund
    Leukocyte specific transcript 1,LST1 (leukocyte-specific transcript 1, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A –, LST1/N) can be detected, some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM very similar to such motifs in Siglec.,LST-1, B144
    Gen-ID
    7940
    UniProt
    O00453
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