CD14 Antikörper

Produktnummer ABIN343181

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-CD14 Antikörper wird verwendet zum Nachweis von CD14 in Proben von Human. Er wurde validiert für FACS, IP und Func.

Kurzübersicht für CD14 Antikörper (ABIN343181)

Target: CD14

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD14 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Produktdetails anti-CD14 Antikörper

Aufreinigung: Protein G purified

Immunogen: Affinity purified recombinant human CD14

Anwendungsinformationen

Applikationshinweise: Suitable for Immunostaining of CD14 positive cells, Immunoprecipitation, Western blot. no significant but small inhibition of LPS binding to human CD14, Binding titre at human CD14+CHO cells (FACS) more than 1:5.000. Recommended working dilution: 1: 100 till 1.000 Binding at mouse CD14 transfected CHO+ cells more than 1:1000 (recommanded working dilution 1:10 til 1:100)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.1 ml without NaN3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-CD14 Antikörper (ABIN343181)

Baveye, Elass, Fernig, Blanquart, Mazurier, Legrand: "Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex." in: Infection and immunity, Vol. 68, Issue 12, pp. 6519-25, (2000) (PubMed).

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund: The antiserum represents a marker for human CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for endotoxin.

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades