USP11 Antikörper

Produktnummer ABIN334288

Produktdetails anti-USP11 Antikörper

Target: USP11 (Ubiquitin Specific Peptidase 11 (USP11))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP11 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Immunogen: Partial peptide of Mouse Usp11

Anwendungsinformationen

Applikationshinweise: IHC: 5.0-10 ug/mL (Paraffin embedded Sections)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/ml

Buffer: PBS [containing 2 % Block Ace as a stabilizer, 0.1 %Proclin as a bacteriostat]

Konservierungsmittel: ProClin

Lagerung: -20 °C

Details zu USP11

Target: USP11 (Ubiquitin Specific Peptidase 11 (USP11))

Andere Bezeichnung: Usp11 (USP11 Produkte)

Synonyme: USP11 antikoerper, DKFZp459L098 antikoerper, UHX1 antikoerper, 6230415D12Rik antikoerper, mKIAA4085 antikoerper, Uhx1 antikoerper, ubiquitin specific peptidase 11 antikoerper, universal stress protein antikoerper, USP11 antikoerper, RR_RS19935 antikoerper, Usp11 antikoerper

Hintergrund: Usp11 (ubiquitin specific peptidase 11) possesses Cys box, His box, Asp and KRF domains, which are highly conserved in many ubiquitin-specific proteases. Usp11 is a ubiquitous protein in various tissues and is primarily localized in the nucleus of non-dividing cells. Usp11 binds specifically to RanBPM which is a RanGTP-binding protein required for correct nucleation of microtubles and inhibits its ubiquitination and degradation. It has been also shown that Usp11 is involved in regulation of the TNFalpha-induced IKKalpha --> p53 signaling pathway and that Usp11 functions in stabilizing HPV-16E7 by reducing ubiquitination and attenuating E7 degradation. Alternate Names: MGC6649, KIAA4085, mKIAA4085, 6230415D12Rik, Usp11 ubiquitin specific peptidase 11.

Gen-ID: 236733