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Activating Transcription Factor 2 (ATF2) (pThr71,pThr53) Antikörper
| Antigen | Activating Transcription Factor 2 (ATF2) |
| Synonyme | HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420 |
| Epitope |
Alternativen pThr71,pThr53 |
| Klonalität | Polyklonal |
| Wirt |
Alternativen Kaninchen |
| Reaktivität |
Alternativen Human |
| Applikation |
Alternativen Enzyme Immunoassay (EIA), Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
|
| Produktnummer | ABIN317966 |
| Menge | 100 µg (1,0 mg/ml) |
| Preis | 320,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Produktmerkmale | Synonyms: ATF-2, CREB2, CREBP1, Activating transcription factor 2, CRE-BP1, HB16, CREB-2, CyclicAMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2,cAMP response element-binding protein CRE-BP1, Cyclic AMP-responsive element-bindingprotein 2 |
| Weitere Bezeichnung | ATF2 |
| Swiss-Prot | P15336 |
| Kreuzreaktivität | Human, Maus, Ratte (Rattus) |
| Beschreibung | Eukaryotic gene transcription is regulated by sequence-specific transcription factors whichbind modular CIS acting promotor and enhancer elements. The cAMP response element(CRE), one of the best studied of such elements, consists of the palindromicoctanucleotide TGACGTCA. Several CRE binding proteins have been identified within theATF/CREB family, the best characterized of which include CREB-1, CREB-2 (also designatedATF-4), ATF-1, ATF-2 and ATF-3. These proteins share highly related COOH terminal leucinezipper dimerization and basic DNA binding domains but are highly divergent in their aminoterminal domains. Although each of the ATF/CREB proteins appear capable of binding CREin its homodimeric form, certain of these also bind as heterodimers, both within theATF/CREB family and even with members of the AP-1 transcription factor family. |
| Spezifität | P-ATF2 (pThr71/53) antibody detects endogenous levels of p-ATF2 protein. Species: Human, Mouse, Rat. Others not tested. |
Anwendungen
| Applikationshinweise | ELISA: 1: 20000~1: 40000. Western Blot: 1: 500~1: 1000. Immunohistochemistry: 1: 50~1: 200. Immunoprecipitation: 1: 50~1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Konzentration | 1,0 mg/ml |
| Reinigung | Aff - Purified |
| Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. |
| Lagerung | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Forschungsgebiet | Zellzyklus, Signaltransduktion, Kinasen/Phosphatasen |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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