CD36 Molecule (thrombospondin Receptor) (CD36) Antikörper

Antigen: CD36 Molecule (thrombospondin Receptor) (CD36)

Synonyme: FAT, GP4, GP3B, GPIV, CHDS7, PASIV, SCARB3

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Rind (Kuh), Hund, Human, Schwein, Kaninchen, Ratte (Rattus)

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN310976

Produktbeschreibung

Weitere Bezeichnung: CD36

Beschreibung: CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in its gene cause platelet glycoprotein deficiency.The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. Keywords: CD36, NM_001001547, NP_001001547, P16671, NM_000072, NP_000063, NM_001001548, NP_001001548, P16671

Anwendungen

Applikationshinweise: ELISA titre: 1:312500 . Western Blotting: Suggested dilution at 1.0 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Forschungsgebiet: Krebs, Artherosklerose, Hämopoetische Vorläufer, Hämatopoetische Stammzellen, CD Antigene, Oberflächenrezeptoren der Immunzellen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-CD36 Molecule (thrombospondin Receptor) (CD36) antibody

anti-CD36 Molecule (thrombospondin Receptor) (CD36) antibody (Image 2)

Publikationen

Publikationen: Ozer, Negis, Aytan et al.: "Vitamin E inhibits CD36 scavenger receptor expression in hypercholesterolemic rabbits." in: Atherosclerosis, Vol. 184, Issue 1, pp. 15-20, 2005 (PubMed).